Table 1. Model (Schaerli et al, 2014) and biological meaning of parameters for the “green” genes of the opposing and concurring gradients networks, respectively
DefinitionNameParameter relates to

Opposing gradients

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a Basal transcription rates from the free promoter
b Transcription rate when LacI is bound
c Binding constant of LacI
n Hill coefficient (multimerisation or cooperativity)

Concurring gradients

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a Basal transcription rate in absence of T7 RNAP
b Transcription rate when T7 RNAP is bound
c Binding constant of T7 RNAP
d Binding constant of LacI
e Transcription rate when T7 RNAP + LacI are bound
f Cooperativity/competition constant of T7 RNAP/LacI
n Hill coefficient (multimerisation or cooperativity)
m Hill coefficient (multimerisation or cooperativity)
  • The complete model for both networks can be found in the Appendix Tables S1 and S2.