Table 1. Novel motility proteins
COGGene locus (ORF)Mutant gene (ortholog)Interacting proteinsMotilityNotes [Refs]
COG1463CJ1648 HP1464MotBRain et al (2001)
COG0082CJ1634CaroC (ECO)FlhA, FlgE2, FliE, FlgK, FliD, FlgB−/+aSee Figure 4
COG0055B3732atpD (ECO)CheZ,CheW, Tsr (E. coli)−/+aArifuzzaman et al (2006)
COG2194CJ0256CJ0256, yjgX (ECO)FlgG‐2aGolden et al (2000)
COG0642CJ1222cCJ1222c (CJE)FliNColoniz.bMacKichan et al (2004)
COG2604CJ1318CJ1318 (CJE)FliN, FliQGolden et al (2000)
NoneHP0488CJ1340c (CJE)FlgE, FlgBFlhA+FlhFc Rain et al (2001); Niehus et al (2004)
COG1923B4172hfq (ECO)FliS, FliL−/+aArifuzzaman et al (2006)
COG0455TP0712 (CJ0063c)HP1034 (HPY)TP0464 (flhF [CJE])van Amsterdam and van der Ende (2004)
COG0457HP1479HP1479 (HPY)FlgBRain et al (2001); Salama et al (2004)
COG0673CJ0504cidh (BSU)FlaGSchumann et al (2001)
COG0791Cj1653clytF (BSU)FliLSchumann et al (2001)
NoneCJ0055crapG (BSU), HP1479 (HPY)FliMSchumann et al (2001); Salama et al (2004)
COG0267TP0209rpmJ (ECO)FliG‐2, CheR, FliY, FlgE, FliS−/+a
COG1774TP0046yaaT (BSU)CheR,FlgD, MetK, FlaB3, TP0959, CheW‐2,Mcp2‐3−/+Schumann et al (2001)
COG0084TP0979ycfH (tatD) (ECO)FliE++aSee Figure 5
COG0346CJ1301ydfO (BSU)FliM, FliYSchumann et al (2001)
COG1512TP0561ydjH (BSU)SigG, FliF, FlhB, FliR, FliQ, FliL−/+a
COG1664TP0048yhbE yhbF (BSU)FliY, FliS−/+aSee Figure 4B
COG2001TP0383yllB (BSU)FliS, FlgK−/+aKobayashi et al (2003)
COG3334CJ1496cylxF (BSU)FliLOperon, domaind Schumann et al (2001)
COG3391TP0421yncE (ECO)TP0567−/+a
COG1699TP0658yviF (BSU)FlaB2, FlaB1, FlaB3aTitz et al (2006)
  • Conserved hypothetical proteins in the columns ‘Gene locus (ORF)’ and ‘Mutant gene (ortholog)’ are predicted to be novel flagellar components, based on their physical interactions with known motility proteins (in T. pallidum, C. jejuni, E. coli, or H. pylori) and their motility phenotype (in E. coli (ECO), H. pylori (HPY), C. jejuni (CJE), or B. subtilis (BSU)). The Motility phenotype refers to the Mutant gene (ortholog): reduced motility ‘−/+’, nonmotile ‘−‘, and increased motility ‘++’. Entries are sorted by ‘Mutant gene’.

  • a This study (Motility phenotype).

  • b Diminished capacity to colonize.

  • c Regulated by FlhA and FlhF.

  • d Flagellum operon, extracellular sensory domain.