Plant Biology
- Linked circadian outputs control elongation growth and flowering in response to photoperiod and temperature
- Daniel D Seaton1,†,
- Robert W Smith14†,
- Young Hun Song25,
- Dana R MacGregor36,
- Kelly Stewart1,
- Gavin Steel1,
- Julia Foreman1,
- Steven Penfield36,
- Takato Imaizumi2,
- Andrew J Millar1 and
- Karen J Halliday*,1
- 1SynthSys and School of Biological Sciences, University of Edinburgh, Edinburgh, UK
- 2Department of Biology, University of Washington, Seattle, WA, USA
- 3Biosciences, University of Exeter, Exeter, UK
- 4Laboratory of Systems & Synthetic Biology, Wageningen UR, Wageningen, The Netherlands
- 5Department of Life Sciences, Ajou University, Suwon, South Korea
- 6Department of Crop Genetics, John Innes Centre, Norwich, UK
- ↵*Corresponding author. Tel: +44 131 651 9083; E‐mail: karen.halliday{at}ed.ac.uk
Crosstalk between the circadian clock and light/temperature signals controls seasonal plant development. Integrated mathematical models of the clock, flowering and elongation pathways identify new behaviours in light and temperature signalling.
Synopsis
Crosstalk between the circadian clock and light/temperature signals controls seasonal plant development. Integrated mathematical models of the clock, flowering and elongation pathways identify new behaviours in light and temperature signalling.
CCA1 negatively regulates FKF1 and CDF1 transcription.
GI has an FKF1‐independent role in CDF1 protein stabilisation.
PIF proteins function throughout light:dark cycles.
Temperature regulates flowering time and hypocotyl elongation pathways at distinct times of day.
Mol Syst Biol. (2015) 11: 776
- Received September 15, 2014.
- Revision received November 21, 2014.
- Accepted December 5, 2014.
- © 2015 The Authors. Published under the terms of the CC BY 4.0 license
This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- An organ boundary‐enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation
- Caihuan Tian1,
- Xiaoni Zhang1,2,
- Jun He1,
- Haopeng Yu1,3,
- Ying Wang1,
- Bihai Shi1,3,
- Yingying Han1,3,
- Guoxun Wang1,3,
- Xiaoming Feng1,
- Cui Zhang1,
- Jin Wang1,3,
- Jiyan Qi1,3,
- Rong Yu2 and
- Yuling Jiao*,1
- 1State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and National Center for Plant Gene Research, Beijing, China
- 2College of Life Sciences, Capital Normal University, Beijing, China
- 3University of Chinese Academy of Sciences, Beijing, China
- ↵*Corresponding author. Tel: +86 10 64807656; Fax: +86 10 64806595; E‐mail: yljiao{at}genetics.ac.cn
The leaf boundary regions separate differentiated organs from undifferentiated stem cells in plants. The gene regulatory network of boundary cells was mapped by combining cell type‐specific genome expression analysis with genomewide yeast one‐hybrid screening.
Synopsis
The leaf boundary regions separate differentiated organs from undifferentiated stem cells in plants. The gene regulatory network of boundary cells was mapped by combining cell type‐specific genome expression analysis with genomewide yeast one‐hybrid screening.
A leaf boundary cell‐specific gene expression map identifies transcriptional signatures and predicts cellular functions.
A genomewide protein–DNA interaction map resolved using a yeast one‐hybrid approach uncovers promoter hubs and predicts new regulating transcription factors (TFs).
An intermediate‐scale experimental test determined the regulatory effects of many TFs on their targets and identified new regulators and regulatory relationships in boundary and axillary meristem formation.
Mol Syst Biol. (2014) 10: 755
- Received June 3, 2014.
- Revision received August 14, 2014.
- Accepted September 24, 2014.
- © 2014 The Authors. Published under the terms of the CC BY 4.0 license
This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Plasma membrane H+‐ATPase regulation is required for auxin gradient formation preceding phototropic growth
- Tim Hohm1,2,†,
- Emilie Demarsy3,†,
- Clément Quan3,
- Laure Allenbach Petrolati3,
- Tobias Preuten3,
- Teva Vernoux4,
- Sven Bergmann*,1,2,‡ and
- Christian Fankhauser*,3,‡
- 1Department of Medical Genetics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
- 2Swiss Institute for Bioinformatics, Lausanne, Switzerland
- 3Centre for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
- 4Laboratoire de Reproduction et Développement des Plantes, CNRS INRA ENS Lyon UCBL Université de Lyon, Lyon, France
- ↵*
Corresponding author. Tel: +41 21 692 5452; E‐mail: sven.bergmann{at}unil.ch
Corresponding author. Tel: +41 21 692 3941; E‐mail: christian.fankhauser{at}unil.ch
In silico and in planta analyses of the contribution of morphological and biophysical parameters to auxin relocalization in phototropism reveal the importance of light‐dependent regulation of apoplastic pH and of cellular topology.
Synopsis
In silico and in planta analyses of the contribution of morphological and biophysical parameters to auxin relocalization in phototropism reveal the importance of light‐dependent regulation of apoplastic pH and of cellular topology.
Regulation of apoplastic pH is a key feature for the establishment of a lateral auxin gradient leading to phototropism.
The phototropin photoreceptors regulate the activity of plasma membrane‐associated H+‐ATPase which are major regulators of apoplastic pH.
Cellular topology has a strong impact on lateral auxin gradient formation.
Mol Syst Biol. (2014) 10: 751
- Received March 2, 2014.
- Revision received August 20, 2014.
- Accepted August 22, 2014.
- © 2014 The Authors. Published under the terms of the CC BY 4.0 license
This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Sequential induction of auxin efflux and influx carriers regulates lateral root emergence
- Benjamin Péret1,2,3,†,
- Alistair M Middleton1,2,4,†,‡,
- Andrew P French1,2,
- Antoine Larrieu1,2,
- Anthony Bishopp1,2,5,
- Maria Njo6,7,
- Darren M Wells1,2,
- Silvana Porco1,2,
- Nathan Mellor1,2,
- Leah R Band1,2,4,
- Ilda Casimiro8,
- Jürgen Kleine‐Vehn6,7,
- Steffen Vanneste6,7,
- Ilkka Sairanen9,
- Romain Mallet1,2,
- Göran Sandberg10,
- Karin Ljung9,
- Tom Beeckman6,7,
- Eva Benkova6,7,
- Jiří Friml6,7,
- Eric Kramer11,
- John R King1,4,
- Ive De Smet2,6,7,
- Tony Pridmore1,
- Markus Owen1,4 and
- Malcolm J Bennett*,1,2
- 1 Centre for Plant Integrative Biology, University of Nottingham, Loughborough, UK
- 2 Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, UK
- 3 Unité Mixte de Recherche 7265, Commissariat à l'Energie Atomique et aux Energies Alternatives, Centre National de la Recherche Scientifique, Aix‐Marseille Université, Laboratoire de Biologie du Développement des Plantes, Saint‐Paul‐lez‐Durance, France
- 4 Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK
- 5 Department of Biosciences, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
- 6 Department of Plant Systems Biology, Flanders Institute for Biotechnology, Ghent, Belgium
- 7 Department of Plant Biotechnology and Genetics, Ghent University, Ghent, Belgium
- 8 Universidad de Extremadura, Facultad de Ciencias, Badajoz, Spain
- 9 Department of Forest Genetics and Plant Physiology, Umeå Plant Science Centre, Swedish University of Agricultural Sciences, Umeå, Sweden
- 10 Department of Plant Physiology, Umeå Plant Science Centre, Umeå University, Umeå, Sweden
- 11 Physics Department, Simon's Rock College, Great Barrington, MA, USA
- ↵*Corresponding author. Centre for Plant Integrative Biology, University of Nottingham, Sutton Bonington Campus, Loughborough, Leics LE12 5RD, UK. Tel.:+44 115 951 3255; Fax:+44 115 951 6334; E‐mail: malcolm.bennett{at}nottingham.ac.uk
↵† These authors contributed equally to this work.
Emergence of a new lateral root primordium through the outer layers of the parental root requires the sequential auxin‐mediated induction of two auxin transporters. This positive feedback regulatory loop coordinates patterned gene expression in outer tissues.
Synopsis
Emergence of a new lateral root primordium through the outer layers of the parental root requires the sequential auxin‐mediated induction of two auxin transporters. This positive feedback regulatory loop coordinates patterned gene expression in outer tissues.
The emergence of lateral roots through several tissues requires the precise regulation of gene expression in overlaying cells to trigger cell separation.
Auxin derived from new lateral root primordia induces a positive feedback loop in the outer tissues by promoting the expression of the auxin influx transporter LAX3.
A mathematical model based on realistic 3D geometries predicted the involvement of an auxin efflux carrier that was later identified to be PIN3.
The model also revealed that PIN3 must be expressed before LAX3 to ensure a ‘robust’ pattern of LAX3 induction in just two overlaying cortical cell files, thereby delimiting cell separation.
Mol Syst Biol. 9: 699
- Received March 15, 2013.
- Accepted August 6, 2013.
- Copyright © 2013 EMBO and Macmillan Publishers Limited
This is an open‐access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.
- A map of cell type‐specific auxin responses
- Bastiaan O R Bargmann1,2,
- Steffen Vanneste3,4,
- Gabriel Krouk5,
- Tal Nawy1,
- Idan Efroni1,
- Eilon Shani2,
- Goh Choe2,
- Jiří Friml3,4,6,
- Dominique C Bergmann7,
- Mark Estelle2 and
- Kenneth D Birnbaum*,1
- 1 Biology Department, Center for Genomics and Systems Biology, New York University, New York, NY, USA
- 2 Department of Cell and Developmental Biology, UCSD, La Jolla, CA, USA
- 3 Department of Plant Systems Biology, VIB, Ghent, Belgium
- 4 Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium
- 5 Laboratoire de Biochimie et Physiologie Moléculaire des Plantes, Institut de Biologie Intégrative des Plantes—Claude Grignon, Montpellier, France
- 6 Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria
- 7 Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA
- ↵*Corresponding author. Biology Department, Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA. Tel.:+1 212 998 8257; Fax:+1 212 995 4015; E‐mail: ken.birnbaum{at}nyu.edu
The transcriptional response to auxin was analyzed in four root cell types. The newly obtained data were cross‐referenced with spatial expression maps to examine auxin's role in regulating gene expression in the root meristem.
Synopsis
The transcriptional response to auxin was analyzed in four root cell types. The newly obtained data were cross‐referenced with spatial expression maps to examine auxin's role in regulating gene expression in the root meristem.
The majority of the thousands of auxin‐responsive genes in the Arabidopsis thaliana root show a spatial bias in their induction or repression by auxin treatment.
Auxin promotes the expression of cell‐identity markers for the developing xylem and quiescent center, whereas it inhibits markers for the maturing xylem, cortex and trichoblasts.
Relative induction or repression by auxin predicts expression along the longitudinal axis of the root.
Mol Syst Biol. 9: 688
- Received March 13, 2013.
- Accepted July 23, 2013.
- Copyright © 2013 EMBO and Macmillan Publishers Limited
This is an open‐access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.
- Plant stem cell maintenance involves direct transcriptional repression of differentiation program
- Ram Kishor Yadav1,2,†,
- Mariano Perales1,†,
- Jérémy Gruel3,4,†,
- Carolyn Ohno5,6,
- Marcus Heisler5,6,
- Thomas Girke1,
- Henrik Jönsson*,3,4 and
- G Venugopala Reddy*,1
- 1 Department of Botany and Plant Sciences, Center for Plant Cell Biology (CEPCEB), Institute of Integrative Genome Biology (IIGB), University of California, Riverside, CA, USA
- 2 Indian Institute of Science Education and Research, Mohali, India
- 3 Computational Biology and Biological Physics Group, Department of Astronomy and Theoretical Physics, Lund University, Lund, Sweden
- 4 Sainsbury Laboratory, University of Cambridge, Cambridge, UK
- 5 European Molecular Biology Laboratory, Heidelberg, Germany
- 6 University of Sydney, Sydney, Australia
- ↵*Corresponding authors. Department of Botany and Plant Sciences, Center for Plant Cell Biology (CEPCEB), Institute of Integrative Genome Biology (IIGB), University of California, Riverside, CA 92521, USA. Tel.:+1 951 8273482; Fax:+1 951 8274437; E‐mail: venug{at}ucr.edu or Sainsbury Laboratory, University of Cambridge, Bateman Street, Cambridge CB2 1LR, UK. Tel.:+44 (0)1223 761128; Fax:+44 (0)1223 350422; E‐mail: henrik{at}thep.lu.se
↵† These authors contributed equally to this work.
The plant stem cell regulator WUSCHEL is shown to repress differentiation‐promoting transcription factors. This regulatory network is analyzed with a computational model of the three‐dimensional shoot stem cell niche and a combination of genetic perturbation and live imaging.
Synopsis
The plant stem cell regulator WUSCHEL is shown to repress differentiation‐promoting transcription factors. This regulatory network is analyzed with a computational model of the three‐dimensional shoot stem cell niche and a combination of genetic perturbation and live imaging.
We find that the transcription factor (TF) WUSCHEL (WUS) directly binds to the promoters and represses a group of genes including key TFs involved in differentiation thus keeping them repressed in the stem cells of the plant shoot, a mechanistic logic that is similar to animal stem cell regulation.
We use a three‐dimensional computational model of the plant shoot stem cell niche to show that the WUS‐mediated repression of the differentiation program along with the previously reported activation of its own negative regulator leads to a robust stem cell homeostasis in a dynamic growth environment.
Live imaging of target genes upon transient manipulation of WUS levels is combined with model perturbations to validate the proposed network and to connect it with a large body of previous experimental work.
Mol Syst Biol. 9: 654
- Received July 25, 2012.
- Accepted February 18, 2013.
- Copyright © 2013 EMBO and Macmillan Publishers Limited
This is an open‐access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.
- Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures
- Peter D Gould1,†,
- Nicolas Ugarte1,†,
- Mirela Domijan2,†,
- Maria Costa2,
- Julia Foreman3,
- Dana MacGregor4,
- Ken Rose3,
- Jayne Griffiths3,
- Andrew J Millar3,5,
- Bärbel Finkenstädt2,
- Steven Penfield4,
- David A Rand2,
- Karen J Halliday3,5 and
- Anthony J W Hall*,1
- 1 Institute of Integrative Biology, University of Liverpool, Liverpool, UK
- 2 Warwick Systems Biology and Mathematics Institute, Coventry House, University of Warwick, Coventry, UK
- 3 SynthSys, Edinburgh, UK
- 4 School of Life Sciences, University of Exeter, Exeter, UK
- 5 School of Biological Sciences, University of Edinburgh, Edinburgh, UK
- ↵*Corresponding author. Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK. Tel.:+44 151 795 4565; Fax:+44 151 795 4403; E‐mail: Anthony.hall{at}liverpool.ac.uk
↵† These authors contributed equally to this work.
Temperature compensation of the Arabidopsis circadian clock is shown to be mediated by the interaction of light and temperature at the level of the crytochrome photoreceptors. These findings reveal that light and temperature share common input mechanisms to the circadian network.
Synopsis
Temperature compensation of the Arabidopsis circadian clock is shown to be mediated by the interaction of light and temperature at the level of the crytochrome photoreceptors. These findings reveal that light and temperature share common input mechanisms to the circadian network.
We provide evidence that blue light signalling via the cryptochromes is important for the temperature‐dependent control of circadian period in plants.
Light and temperature converge upon common targets in the circadian network.
We have constructed a temperature‐compensated model of the plant circadian clock by adding a temperature effect to a subset of light‐sensitive processes.
The model matches experimental data and predicted a temperature‐dependent change in the protein level of a key clock gene.
Mol Syst Biol. 9: 650
- Received June 27, 2012.
- Accepted January 28, 2013.
- Copyright © 2013 EMBO and Macmillan Publishers Limited
This is an open‐access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.
- Systems‐based analysis of Arabidopsis leaf growth reveals adaptation to water deficit
- Katja Baerenfaller*,1,†,
- Catherine Massonnet2,†,‡,
- Sean Walsh1,†,
- Sacha Baginsky1,§,
- Peter Bühlmann3,
- Lars Hennig1,4,
- Matthias Hirsch‐Hoffmann1,
- Katharine A Howell5,
- Sabine Kahlau5,6,
- Amandine Radziejwoski7,||,
- Doris Russenberger1,
- Dorothea Rutishauser8,¶,
- Ian Small5,
- Daniel Stekhoven3,9,
- Ronan Sulpice6,
- Julia Svozil1,
- Nathalie Wuyts2,††,
- Mark Stitt6,
- Pierre Hilson*,7,10,
- Christine Granier*,2 and
- Wilhelm Gruissem*,1,8
- 1 Department of Biology, ETH Zurich, Zurich, Switzerland
- 2 Laboratoire d'Ecophysiologie des Plantes sous Stress Environnementaux (LEPSE), INRA‐AGRO‐M, Montpellier Cedex, France
- 3 Seminar for Statistics, ETH Zurich, Zurich, Switzerland
- 4 Department of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden
- 5 Plant Energy Biology, ARC Centre of Excellence, The University of Western Australia, Crawley, Western Australia, Australia
- 6 Max Planck Institute of Molecular Plant Physiology, Golm, Germany
- 7 Department of Plant Systems Biology, VIB, Gent, Belgium
- 8 Functional Genomics Center Zurich, Zurich, Switzerland
- 9 Competence Center for Systems Physiology and Metabolic Diseases, Zurich, Switzerland
- 10 Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium
- ↵*Corresponding authors. Department of Biology, ETH Zurich, CH‐8092 Zurich, Switzerland. Tel.:+ 41 446323866; Fax:+41 446321044; E-mail: bkatja{at}ethz.chDepartment of Biology, ETH Zurich, CH‐8092 Zurich, Switzerland. Tel.:+ 41 446320857; Fax:+41 446321079; E-mail: wgruissem{at}ethz.chDepartment of Plant Systems Biology, VIB, B‐9051 Gent, Belgium. Tel.:+ 32 93313830; Fax:+32 93313809; E-mail: pihil{at}psb.vib-ugent.beLaboratoire d'Ecophysiologie des Plantes sous Stress Environnementaux (LEPSE), INRA‐AGRO‐M, F‐34060 Montpellier Cedex 1, France. Tel.:+ 33 499612950; Fax:+33 467522116; E-mail: granier{at}supagro.inra.fr
↵† These authors contributed equally to this work
Deep profiling of the transcriptome and proteome during leaf development reveals unexpected responses to water deficit, as well as a surprising lack of protein‐level fluctuations during the day–night cycle, despite clear changes at the transcript level.
Synopsis
Deep profiling of the transcriptome and proteome during leaf development reveals unexpected responses to water deficit, as well as a surprising lack of protein‐level fluctuations during the day–night cycle, despite clear changes at the transcript level.
Transcript and protein variation patterns reflect the functional stages of the leaf.
Protein and transcript levels correlate well during leaf development, with some notable exceptions.
Diurnal transcript‐level fluctuations are not matched by corresponding diurnal fluctuations in the detected proteome.
Continuous reduced soil water content results in reduced leaf growth, but the plant adapts at molecular levels without showing a typical drought response.
Mol Syst Biol. 8: 606
- Received April 11, 2012.
- Accepted July 25, 2012.
- Copyright © 2012 EMBO and Macmillan Publishers Limited
This is an open‐access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.
- The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops
- Alexandra Pokhilko1,
- Aurora Piñas Fernández1,
- Kieron D Edwards1,†,
- Megan M Southern2,
- Karen J Halliday1,3 and
- Andrew J Millar*,1,3
- 1 School of Biological Sciences, University of Edinburgh, Edinburgh, UK
- 2 Department of Biological Sciences, University of Warwick, Coventry, UK
- 3 SynthSys Edinburgh, University of Edinburgh, Edinburgh, UK
- ↵*Corresponding author. SynthSys Edinburgh, University of Edinburgh, CH Waddington Building, Kings Buildings, Mayfield Road, Edinburgh EH9 3JD, UK. Tel.: +44 131 651 3325; Fax: +44 131 651 9068; E-mail: >andrew.millar{at}ed.ac.uk
Recent findings are incorporated into a new mathematical model of the plant circadian clock, revealing a complex circuit structure comprised of multiple negative feedback loops, and predicting a repressive role for a key regulator, TOC1, which the authors confirm experimentally.
Synopsis
Recent findings are incorporated into a new mathematical model of the plant circadian clock, revealing a complex circuit structure comprised of multiple negative feedback loops, and predicting a repressive role for a key regulator, TOC1, which the authors confirm experimentally.
The feedback structure of the plant clock's evening loop was reconstructed based on multiple data, and is now represented by the evening complex (ELF3‐ELF4‐LUX), which represses transcription from the ELF4 and LUX promoters.
Computational analysis of timeseries data from mutant plants predicts that TOC1 is a repressor of the key morning genes LHY and CCA1, not an activator. Analysis of LHY and CCA1 expression in TOC1 gain‐ and loss‐of‐function plants confirms this prediction.
Light induction of LHY and CCA1 expression is predicted to determine the clock's response to brief light pulses, matching the observed phase‐response curve.
The evening complex controls LHY and CCA1 expression by a double‐negative connection, rather than direct activation, forming part of a three‐component repressilator circuit, which is itself only part of the more complex circuit of the clock system.
Mol Syst Biol. 8: 574
- Received August 9, 2011.
- Accepted February 13, 2012.
- Copyright © 2012 EMBO and Macmillan Publishers Limited
This is an open‐access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.
- Widespread translational control contributes to the regulation of Arabidopsis photomorphogenesis
- 1 Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan, ROC
- 2 Molecular and Biological Agricultural Sciences Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan, ROC
- 3 Department of Life Sciences, Graduate Institute of Biotechnology, National Chung‐Hsing University, Taichung, Taiwan, ROC
- ↵*Corresponding author. Institute of Plant and Microbial Biology, Academia Sinica, 128, Sec 2, Academia Road, Taipei 11529, Taiwan, ROC. Tel./Fax: +886 2 2787 1178; E-mail: shuwu{at}gate.sinica.edu.tw
Environmental light regulates and optimizes plant growth and development. Genomic profiling of polysome‐associated mRNA reveals that light stimulates dramatic changes in translational regulation, which contribute more to light‐induced gene expression changes than transcriptional regulation.
Synopsis
Environmental light regulates and optimizes plant growth and development. Genomic profiling of polysome‐associated mRNA reveals that light stimulates dramatic changes in translational regulation, which contribute more to light‐induced gene expression changes than transcriptional regulation.
Translational control has a stronger impact on gene expression regulation than transcriptomic changes during photomorphogenesis in Arabidopsis.
Transcriptional and translational regulations have complementary and distinct impacts on biochemical pathways and biological processes.
Light‐mediated translational control prefers stable and shorter mRNAs.
mRNAs with TAGGGTTT in their 5′ untranslated region have higher translatability.
Mol Syst Biol. 8: 566
- Received May 30, 2011.
- Accepted November 25, 2011.
- Copyright © 2012 EMBO and Macmillan Publishers Limited
This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
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